Computational Biologist at Stanford Univeristy.
Background and Interests:
Currently working at the Satpathy Lab leveraging single cell datasets to derive novel insights in normal health and disease. Additionally provide computational and analytics support to members of the lab to assist in a variety of data types and research questions.
- mtscATAC-seq
- Perturb-seq
- ASAP-seq
- NanoString CosMX Spatial Transcriptomics
- etc.
Previously worked in Maslen Lab at Oregon Health & Science University studying Geneticically Triggered Aortic Aneurysms.
- NGS Sequencing including Whole Exome sequencing, Targeted and Whole Genome Bisulfite Sequencing
- Genetically Triggered Aortopathy in Turner Syndrome.
- DNA methylation analysis and visualization.
Current Projects:
My current research interests include:
1) Longitudinal mitochondrial lineage tracing of blood in healthy donors.
2) Ongoing interest in characterizing Turner Syndrome with single cell sequencing to gain insight into both rare and common disease.
3) Cell type of origin of Tubal-Ovarian Cancer in collaboration with Dr. Brooke Howitt.
4) Epigenomic landscape of CD8+ tissue-resident memory T cells
5) Latent human herpesvirus 6 reactivation in chimeric antigen receptor T cells.
6+) Various projects utilizing single cell multi-omic profiling.
Previous research interests:
1) Thesis Project explores epigenetic alterations in DNA methylation related to Bicuspid Aortic Valve in Turner Syndrome.
2) Thesis Project includes bioinformatics analysis to characterized the newly released Illumina Methyl-Capture seq platform.
3) Deep Learning Project: Predict Genes undergoing Genetic Compensation (w/ RNA-seq data) using DNA sequence information.